Assessment of Liver Function among Patients with Rheumatoid Arthritis Versus Patients with Psoriatic Arthritis Treated by Methotrexate

Background:Hepatotoxicity is a well-known adverse effect of methotrexate therapy.
 Objective: To assess liver functions such as ALT and AST in patients with rheumatoid arthritis psoriatic receiving compare the those cured by using methotrexate.
 Patients Methods: This observational, cross-sectional analysis involved 50 RA who satisfied EULAR-ACR-2010 standards for PSA cases fulfilled CASPAR classification criteria PSA, constant weekly MTX therapy (oral or parenteral) up to 25mg, together folic acid, function parameters were estimated compared.
 Results: 78% 100 participants enrolled this study females. 10% smokers, but there was no significant difference between two groups (p = 0.410). None alcoholics. There regarding type medications. 42% group on other medications compared 2% < 0.001). The mean (26.0 IU/L) considerably 0.005) greater than (19.6 which shows an insignificant 0.055) change means (26.3 IU/L matched 20.6 participants).
 Conclusion: Our research data that treated had higher level when patients.